HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 86656960, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 86656924 | HCID 86656924 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86656960 | HCID 86656960 | 88.2% |
Reaction Steps
2-(6-Chloro-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid ((S)-1-methyl-pyrrolidin-3-yl)amide (35 mg) was prepared by following General Procedure P starting from 2-(6-chloro-benzothiazol-2-ylamino)-1-methyl-1H-benzoimidazole-5-carboxylic acid (S)-pyrrolidin-3-ylamide dihydrochloride (45 mg), 37% formaldehyde (500 uL), and Na(OAc)3BH (32 mg) in DCM (500 uL). LC/MS: m/z 440.7.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-dee8bf892e4c42f99b703d2912d916a6 |
| Source note | uspto-grants-2014_06 |