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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411048Generated: October 25, 2026

Methylamine → 4-(Methylamino)-3-nitrobenzoic acid

https://huagongshe.com/reaction/411048

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant4-Fluoro-3-nitrobenzoic acidHCID 67987—
SolventTetrahydrofuranHCID 8028—
Product4-(Methylamino)-3-nitrobenzoic acidHCID 283475—

Reaction Steps

4-Methylamino-3-nitro-benzoic acid (25 g) was prepared by following general procedure A starting from 4-fluoro-3-nitro-benzoic acid (25 g) and 2 M methylamine in THF (100 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08759535B2
Source datasetuspto-grants-2014_06
ORD IDord-bf684826d13c436bb75566d70320a486
Source noteuspto-grants-2014_06