HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl ester → (4-Methylamino-3-nitro-benzoylamino)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl ester | HCID 67332520 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Product | (4-Methylamino-3-nitro-benzoylamino)-acetic acid | HCID 67334647 | 81.4% |
Reaction Steps
(4-Methylamino-3-nitro-benzoylamino)-acetic acid (800 mg) was prepared starting from (4-methylamino-3-nitro-benzoylamino)-acetic acid tert-butyl ester (1.2 g) in 4 M HCl-dioxane (2 mL) and DCM (2 mL). The reaction was stirred at room temperature for 8 h. The solvent was evaporated to isolate pure compound without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08759535B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-040cee8d28ca45deb8dd242cb4abb8bb |
| Source note | uspto-grants-2014_06 |