反应详情

A solution of 7-methylindoline (10.2 g) in acetic anhydride (25 ml) was refluxed for 30 min. After cooling, the reaction solution was poured into ice water (250 ml) and the resulting crystal was filtered by means of suction, heated and vacuum dried to yield the end product (11.7 g).

1. temperatureAfter cooling
2. filtrationthe resulting crystal was filtered by means of suction
3. temperatureheated
4. customvacuum dried