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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411313Generated: October 28, 2026

(1S,2R)-(-)-1-Amino-2-indanol → 1-(S)-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-2-(R)-indanol

https://huagongshe.com/reaction/411313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,2R)-(-)-1-Amino-2-indanolHCID 9866743—
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
Product1-(S)-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-2-(R)-indanolHCID 86584965—

Reaction Steps

Following the General Procedure C and using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and 1-(S)-amino-2-(R)-indanol, the title compound was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559141B2
Source datasetuspto-grants-2003_05
ORD IDord-4071b319bd0e46668881c7e5d24437f8
Source noteuspto-grants-2003_05