HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(Phenylacetyl)-L-alanine → 3-(N'-(Phenylacetyl)-alaninyl)amino-epsilon-caprolactam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(Phenylacetyl)-L-alanine | HCID 7004640 | — |
| Reactant | 4-Aminoazepan-2-one | HCID 21584138 | — |
| Product | 3-(N'-(Phenylacetyl)-alaninyl)amino-epsilon-caprolactam | HCID 10215097 | — |
Reaction Steps
Following General Procedure B above using N-(phenylacetyl)-L-alanine (Example A) and 3-amino-ε-caprolactam (Sigma), the title compound was prepared as a solid having a melting point of 200-202° C. The reaction was monitored by tlc on silica gel (Rf=0.30 in 1:9 methanol/dichloromethane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06559141B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-1a048ab14f2e4ff8a667c68f271e455f |
| Source note | uspto-grants-2003_05 |