HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyl pyruvate → N-(4-azidophenyl)alanine Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyl pyruvate | HCID 83084 | — |
| Reactant | 4-Azidoaniline | HCID 84674 | — |
| Product | N-(4-azidophenyl)alanine Iso-butyl Ester | HCID 54176542 | — |
Reaction Steps
Following General Procedure AA above and using 4-azidoaniline (Aldrich) and iso-butyl pyruvate (prepared by following General Procedure AO above), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.3 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06559141B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-882b12eb691540ff82b4e9ad38f8502c |
| Source note | uspto-grants-2003_05 |