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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411484Generated: October 27, 2026

2-Thiopheneacetic acid → 2-[(2-Thienyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/411484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetic acidHCID 15970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Thienyl)acetamido]butyric acid isobutyl esterHCID 54443682—

Reaction Steps

Following General Procedure BI above and using 2-thiopheneacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559141B2
Source datasetuspto-grants-2003_05
ORD IDord-18a4bdf52a5a4c90841553ab1bae0f6c
Source noteuspto-grants-2003_05