Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411490Generated: October 30, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/411490

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl EsterHCID 15481782—

Reaction Steps

Following General Procedure BI above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS #19668-85-0) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559141B2
Source datasetuspto-grants-2003_05
ORD IDord-71a2e5fc27714b0e919f375d8facc6ff
Source noteuspto-grants-2003_05