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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411496Generated: October 26, 2026

p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

https://huagongshe.com/reaction/411496

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(4-methylphenyl)acetyl]alanine iso-butyl esterHCID 53936136—

Reaction Steps

Following General Procedure BI above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559141B2
Source datasetuspto-grants-2003_05
ORD IDord-3c9e1979697d4ac6aed9c6e2eb1ead8e
Source noteuspto-grants-2003_05