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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411623Generated: October 31, 2026

Sodium Cyanide → HCID 69555828, compound

https://huagongshe.com/reaction/411623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CyanideHCID 8929—
Reactant3-ThiophenecarboxaldehydeHCID 68135—
ReactantTosylmethyl isocyanideHCID 161915—
ProductHCID 69555828HCID 69555828—

Reaction Steps

In a manner analogous to Preparation 1, 3-thiophene carboxaldehyde (0.35 mL, 3.99 mmol), tosylmethylisocyanide (0.75 g, 3.84 mmol) and NaCN (0.02 g, 0.40 mmol) gave the desired compound as a tan solid. MS(ES+) m/z 614.8 (2M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559172B1
Source datasetuspto-grants-2003_05
ORD IDord-5cde8d4fbec44dcaaa349d425d8f7219
Source noteuspto-grants-2003_05