HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-phenyl-1H-pyrazol-5-amine → HCID 178517164, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-phenyl-1H-pyrazol-5-amine | HCID 594319 | — |
| Reactant | HCID 178418806 | HCID 178418806 | — |
| Reactant | HCID 178517101 | HCID 178517101 | — |
| Reactant | HCID 178517165 | HCID 178517165 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178517164 | HCID 178517164 | — |
Reaction Steps
The named compound is prepared by substituting E & Z-3-[(hydroxy)-methylene]-5-chloro-1,3-dihydro-indol-2-one for E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one and 4-bromo-5-phenyl-1H-pyrazol-3-ylamine for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-5-chloro-1,3-dihydro-indol-2-one (0.1820 gms.) is reacted with 0.4511 gms. of 4-bromo-5-phenyl-1H-pyrazol-3-ylamine by refluxing in tetrahydrofuran (3.0 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06559173B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-b0a8ba0eebec43e5920d546093ddbc02 |
| Source note | uspto-grants-2003_05 |