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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 411678Generated: October 31, 2026

4-fluoro-1H-indazol-3-amine → HCID 178517097, compound

https://huagongshe.com/reaction/411678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-fluoro-1H-indazol-3-amineHCID 817911—
ReactantHCID 178418806HCID 178418806—
ReactantHCID 178517101HCID 178517101—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178517097HCID 178517097—

Reaction Steps

The named compound is prepared by substituting 4-fluoro-1H-indazol-3-ylamine for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one (0.100 gms.) is reacted with 0.2186 gms. of 4-fluoro-1H-indazol-3-ylamine by refluxing in tetrahydrofuran (2.5 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06559173B1
Source datasetuspto-grants-2003_05
ORD IDord-ffdaf8574f084e538a695a417b3cd828
Source noteuspto-grants-2003_05