Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Decanoic Acid | HCID 2969 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Chloromethyl chlorosulfate | HCID 2733556 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Solvent | Water | HCID 962 | — |
| Product | Chloromethyl decanoate | HCID 572571 | 100% |
Reaction Steps
Decanoic acid (0.2 gm, 1.2 mmol) was treated with 4 eq NaHCO3, 0.1 eq Bu4NHSO4 and, 1.2 eq ClCH2OSO2Cl in 1:1 CH2Cl2:H2O. The reaction was stirred vigorously at 0° C. for 30 min then room temperature (“RT”) for 3 hrs. Aqueous workup yielded chloromethyldecanoate (yield 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06559164B1 |
|---|
| Source dataset | uspto-grants-2003_05 |
|---|
| ORD ID | ord-01ffc514e7334937b06f28c9c7eef12f |
|---|
| Source note | uspto-grants-2003_05 |
|---|
