2-Ethoxybenzoyl chloride → 3-Carbamoyl-2-(2-ethoxybenzamido)benzamide

HRID 412044Notes

Reaction equation

HRID 412044 reaction equation
[NH2:1][C:2]1[C:10]([C:11](=[O:13])[NH2:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[CH2:14]([O:16][C:17]1[CH:25]=[CH:24][CH:23]=[CH:22][C:18]=1[C:19](Cl)=[O:20])[CH3:15]>>[C:4]([C:3]1[C:2]([NH:1][C:19](=[O:20])[C:18]2[CH:22]=[CH:23][CH:24]=[CH:25][C:17]=2[O:16][CH2:14][CH3:15])=[C:10]([CH:9]=[CH:8][CH:7]=1)[C:11]([NH2:12])=[O:13])(=[O:5])[NH2:6]

Participants

3

Reactant 2

HCID 30163972-Ethoxybenzoyl chlorideHCID 102413842-Aminobenzene-1,3-dicarboxamide

Product 1

HCID 185365653-Carbamoyl-2-(2-ethoxybenzamido)benzamide

Procedure

The title compound was prepared from 2-amino-3-carbamoylbenzamide and 2-ethoxybenzoyl chloride following the procedure of Preparation 5 and was obtained as colourless crystals (33%), m.p. 224-225° C.

Workup

  1. customthe procedure of Preparation 5

Sources & evidence

ORD record
ord-037a2fddfdc84bafbde8bfee1314d7c9
Source dataset
uspto-grants-2003_05
Patent number
US06562830B1

Reaction notes

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