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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412060Generated: November 1, 2026

Potassium Carbonate → HCID 18536301, compound

https://huagongshe.com/reaction/412060

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl 2-chloronicotinateHCID 819931—
Reactant2-Piperazinylpyrimidine dihydrochlorideHCID 11680272—
SolventDimethylformamideHCID 6228—
ProductHCID 18536301HCID 18536301—

Reaction Steps

3.4 g of methyl chloronicotinate, 11.1 g of potassium carbonate and 4.7 g of N-(2-pyrimidyl)piperazine dihydrochloride were reacted in 75 ml of DMF analogously to Example 1a, 4.6 g (78%) of the product being obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562827B1
Source datasetuspto-grants-2003_05
ORD IDord-f25a856c40ea47d88c92a75f8e1b53eb
Source noteuspto-grants-2003_05