HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 2-(4-benzylpiperazin-1-yl)nicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Reactant | Methyl 2-chloronicotinate | HCID 819931 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2-(4-benzylpiperazin-1-yl)nicotinate | HCID 18536282 | — |
Reaction Steps
3.4 g of methyl 2-chloronicotinate, 5.5 g of potassium carbonate and 3.5 g of N-benzylpiperazine were reacted in 75 ml of DMF analogously to Example 1a, 6.2 g (100%) of the product being obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562827B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-db759a24a04441af8763a76023778cd3 |
| Source note | uspto-grants-2003_05 |