HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18536094, compound → HCID 18536159, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18536094 | HCID 18536094 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | HCID 18536159 | HCID 18536159 | — |
Reaction Steps
To a solution of the benzyl ether from Step B (240 mg, 0.43 mmol) in 4 mL of 1:1 MeOH/EtOAc was added 10% palladium on carbon (240 mg). The solution was stirred under a balloon atmosphere of hydrogen at room temperature. After 16 hours, the solution was filtered through celite. Concentration in vacuo provided the titled which was used in the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562823B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-bdbe32f462a84f3e94a8476e456ffd36 |
| Source note | uspto-grants-2003_05 |