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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412144Generated: October 30, 2026

HCID 18536094, compound → HCID 18536159, compound

https://huagongshe.com/reaction/412144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18536094HCID 18536094—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthylacetate methanolHCID 21584119—
ProductHCID 18536159HCID 18536159—

Reaction Steps

To a solution of the benzyl ether from Step B (240 mg, 0.43 mmol) in 4 mL of 1:1 MeOH/EtOAc was added 10% palladium on carbon (240 mg). The solution was stirred under a balloon atmosphere of hydrogen at room temperature. After 16 hours, the solution was filtered through celite. Concentration in vacuo provided the titled which was used in the next reaction without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562823B1
Source datasetuspto-grants-2003_05
ORD IDord-bdbe32f462a84f3e94a8476e456ffd36
Source noteuspto-grants-2003_05