1-(4-Cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde → 1-(4-Cyano-3,5-dichlorobenzyl)-5-imidazolecarboxaldehyde

HRID 412148Notes

Reaction equation

HRID 412148 reaction equation
[C:1]([C:3]1[C:10]([Cl:11])=[CH:9][C:6]([CH2:7]Br)=[CH:5][C:4]=1[Cl:12])#[N:2].C(C1C=CC(C[N:20]2[C:24]([CH:25]=[O:26])=[CH:23][N:22]=[CH:21]2)=CC=1F)#N>>[C:1]([C:3]1[C:10]([Cl:11])=[CH:9][C:6]([CH2:7][N:20]2[C:24]([CH:25]=[O:26])=[CH:23][N:22]=[CH:21]2)=[CH:5][C:4]=1[Cl:12])#[N:2]

Participants

3

Reactant 2

HCID 114247081-(4-Cyano-3-fluorobenzyl)-5-imidazolecarboxaldehydeHCID 185361844-(Bromomethyl)-2,6-dichlorobenzonitrile

Product 1

HCID 185361351-(4-Cyano-3,5-dichlorobenzyl)-5-imidazolecarboxaldehyde

Procedure

The titled product was prepared from the product of Step C using the same procedures as those described in Example 1, Steps D through G for the preparation of 1-(4-cyano-3-fluorobenzyl)-5-imidazolecarboxaldehyde.

Sources & evidence

ORD record
ord-6239268bec174954a251cbb5033719c8
Source dataset
uspto-grants-2003_05
Patent number
US06562823B1

Reaction notes

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