Triethylamine → HCID 18536039, compound

Participants

Reaction Steps

To a solution of the crude product from Step A (52.6 mmol) in 150 mL of dichloromethane at 0° C. was added triethylamine (14.66 mL, 105 mmol), followed by methanesulfonyl chloride (6.52 mL, 84.3 mmol). After 30 minutes, the reaction was poured into EtOAc and washed with water, saturated NH4Cl solution, saturated NaHCO3 solution, and brine, dried (Na2SO4), filtered, and concentrated in vacuo. The product was isolated as a white solid which was used without further purification.

Provenance & Evidence