3-Methylsulfonyl-4-trifluoromethoxynitrobenzene → 3-Methylsulfonyl-4-trifluoromethoxyaniline

Participants

Reaction Steps

3-Methylsulfonyl-4-trifluoromethoxynitrobenzene (17.5 g) was dissolved in methanol (400 mL) followed by addition of palladium on carbon (10%, 50% water, 3.2 g). The reaction mixture was hydrogenated for 17 hours at 1 atm of hydrogen, filtered and concentrated in vacuo to give 14.3 g of 3-methylsulfonyl-4-trifluoromethoxyaniline.

Provenance & Evidence