Chloroform → HCID 18536377, compound

Participants

Reaction Steps

To a solution of 2-[N-[4-(1-tert-butoxycarbonylpiperidin-4-yloxy)phenyl]-N-(4-methoxycarbonylbenzoyl)aminomethyl]-1-(cyclohexylcarbamoylmethyl)-benzimidazole-5-carboxamidine (201 mg) in chloroform (1 ml) was added trifluoroacetic acid (1 ml), and the mixture was stirred for 5 min. After completion of the reaction, the solvent was evaporated and to the obtained residue was added a 1N hydrogen chloride-diethyl ether solution. The obtained solid was collected by filtration and dried under reduced pressure to give the title compound (175 mg).

Provenance & Evidence