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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412657Generated: October 26, 2026

Lithium Hydroxide → (2S)-1-(6-bromo-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acid

https://huagongshe.com/reaction/412657

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactantmethyl (2S)-1-(6-bromo-1,3-benzoxazol-2-yl)-2-piperidinecarboxylateHCID 9949771—
Product(2S)-1-(6-bromo-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acidHCID 57232818—

Reaction Steps

The title compound was prepared by a similar method to Preparation 3 from methyl (2S)-1-(6-bromo-1,3-benzoxazol-2-yl)-2-piperidinecarboxylate [see Preparation 5] and 1N aqueous lithium hydroxide solution, to afford (2S)-1-(6-bromo-1,3-benzoxazol-2-yl)-2-piperidinecarboxylic acid as a pink foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562964B1
Source datasetuspto-grants-2003_05
ORD IDord-e7c777a45d0042b18dc797e2d0cd1a50
Source noteuspto-grants-2003_05