HCID 22669971, compound → HCID 22669984, compound

Participants

Reaction Steps

190 mg of the alcohol obtained in Stage C of Example 8, 50 mg of palladium on carbon at 9.5% and 30 ml of ethyl acetate are mixed together for 15 minutes under a hydrogen atmosphere at ambient temperature. After filtration and evaporation under reduced pressure, the crude product is purified by chromatography eluting with a cyclohexane/ethyl acetate mixture 95/5. In this way 45 mg of expected product is obtained.

Provenance & Evidence