Methanol → HCID 9900622, compound

HRID 412850Notes

Reaction equation

HRID 412850 reaction equation
O=S(Cl)Cl.[N+:5]([C:8]1[CH:9]=[C:10]([CH:14]=[C:15]([N+:18]([O-:20])=[O:19])[C:16]=1Cl)[C:11]([OH:13])=O)([O-:7])=[O:6].[CH3:21][OH:22]>>[N+:18]([C:15]1[CH:14]=[C:10]([CH2:11][OH:13])[CH:9]=[C:8]([N+:5]([O-:7])=[O:6])[C:16]=1[C:8]1[CH:9]=[CH:10][C:21]([OH:22])=[CH:15][CH:16]=1)([O-:20])=[O:19]

Participants

4

Reactant 3

HCID 887Methanol2×HCID 83774-Chloro-3,5-dinitrobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 9900622HCID 9900622, compound

Procedure

2.96 ml of SOCl2 is added at 0° C., under an inert atmosphere and dropwise to 10 g of 3,5-dinitro-4-chlorobenzoic acid (JANSSEN) in 150 ml of methanol and agitation is carried out under reflux of methanol for 2 hours then for 15 hours at ambient temperature. The reaction medium is poured into ice and precipitation of the product is observed. After drying, 10.3 g of expected product is obtained.

Workup

  1. additionThe reaction medium is poured into ice and precipitation of the product
  2. customAfter drying

Sources & evidence

ORD record
ord-c7b3d849b2944833a097def742c02b02
Source dataset
uspto-grants-2003_05
Patent number
US06563008B2

Reaction notes

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