Acetic Acid → HCID 54063239, compound

Participants

Reaction Steps

Sodium methoxide (134 mg, 2.5 mmol) was added to a solution of Compound 10 (10.84 g, 24.9 mmol) in methanol (30 ml), and the mixture was stirred at room temperature under nitrogen gas atmosphere for 48 hours. The reaction mixture was neutralized with acetic acid, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (toluene:ethyl acetate=4:1) to obtain Compound 11 (6.8 g, 78%).

Provenance & Evidence