Ammonium cerium (IV) nitrate → HCID 53840937, compound

Participants

Reaction Steps

Compound 22 (9.0 g, 14.1 mmol) was dissolved in acetonitrile:water (4:1, 400 ml). Ammonium cerium (IV) nitrate (20.1 g, 36.7 mmol) was added thereto, and the mixture was stirred vigorously for 40 minutes at room temperature. The reaction mixture was diluted with ethyl acetate, washed successively with water, saturated aqueous sodium hydrogencarbonate, and saturated brine, and dried over magnesium sulfate. The solvent was evaporated under reduced pressure. The residue was purified by silica, gel column chromatography (toluene:ethyl acetate=2.5:1) to obtain Compound 23 (6.1 g, 81%).

Provenance & Evidence