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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 412879Generated: October 30, 2026

Pyrazole → HCID 18538721, compound

https://huagongshe.com/reaction/412879

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazoleHCID 1048—
ReactantTert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 2764081—
ProductHCID 18538721HCID 18538721—

Reaction Steps

By a similar manner to Reference Example 29, 1-tert-butoxycarbonyl-piperidin-4-methanol (1.08 g, 5.0 mmol) was reacted with pyrazole (1.02 g, 1.5 mmol) to give the titled compound as pale yellow oily substance (980 mg, 74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06562978B1
Source datasetuspto-grants-2003_05
ORD IDord-dea9ac6031b4492fa5112fa7273096c5
Source noteuspto-grants-2003_05