HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-hydroxypiperidine-1-carboxylate → Tert-butyl 4-(pyridin-4-yloxy)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-hydroxypiperidine-1-carboxylate | HCID 643502 | — |
| Reactant | HCID 178418642 | HCID 178418642 | — |
| Product | Tert-butyl 4-(pyridin-4-yloxy)piperidine-1-carboxylate | HCID 21906087 | — |
Reaction Steps
By a similar manner to Reference Example 35, 1-tert-butoxycarbonyl-4-hydroxypiperidine (1.01 g, 5.0 mmol) was reacted with 4-hydroxypyridine (0.57 g, 6.0 mmol) to give the titled compound as pale yellow solid substance(1.05 g, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06562978B1 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-f1f91ba56f1b47498d8e60f48908182a |
| Source note | uspto-grants-2003_05 |