4-Fluorobenzoyl chloride → HCID 11578088, compound

HRID 412955Notes

Reaction equation

HRID 412955 reaction equation
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][N:11]([C:24]2[CH:29]=[CH:28][C:27]([Cl:30])=[C:26]([Cl:31])[CH:25]=2)[C:12]([CH:14]2[CH2:19][CH2:18][N:17]([S:20]([CH3:23])(=[O:22])=[O:21])[CH2:16][CH2:15]2)=[O:13])[CH2:4][CH2:3]1.[F:32][C:33]1[CH:41]=[CH:40][C:36]([C:37](Cl)=[O:38])=[CH:35][CH:34]=1>>[Cl:31][C:26]1[CH:25]=[C:24]([N:11]([CH2:10][CH2:9][CH2:8][N:5]2[CH2:6][CH2:7][CH:2]([NH:1][C:37](=[O:38])[C:36]3[CH:40]=[CH:41][C:33]([F:32])=[CH:34][CH:35]=3)[CH2:3][CH2:4]2)[C:12]([CH:14]2[CH2:19][CH2:18][N:17]([S:20]([CH3:23])(=[O:21])=[O:22])[CH2:16][CH2:15]2)=[O:13])[CH:29]=[CH:28][C:27]=1[Cl:30]

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 11548627HCID 11548627, compound

Product 1

HCID 11578088HCID 11578088, compoundYield 34%

Procedure

The title compound was prepared using a similar procedure to that described in example 195 from the title compound of example 199 and 4-fluorobenzoyl chloride. Yield 34%.

Sources & evidence

ORD record
ord-f68f48ab1d584dcba62d4ad5c87ec606
Source dataset
uspto-grants-2003_05
Patent number
US06562978B1

Reaction notes

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