HCID 10658069, compound → HCID 67753878, compound
Reaction equation
[OH:1][C@@H:2]1[C@@H:8]2[C@@H:5]([C:6](=[O:20])[N:7]2CC2C=CC(OC)=C(OC)C=2)[N:4]([C:21]([O:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:22])[CH2:3]1.O=C1[C@@H]2[C@@H](CCN2C(OCC2C=CC=CC=2)=O)N1>>[OH:1][C@@H:2]1[C@@H:8]2[C@@H:5]([C:6](=[O:20])[NH:7]2)[N:4]([C:21]([O:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:22])[CH2:3]1Participants
3
Procedure
Benzyl (1S,4S,5S)-4-hydroxy-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylate was prepared from benzyl (1S,4S,5S)-4-hydroxy-6-(3,4-dimethoxybenzyl)-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylate (Example 1) in the same manner as described for benzyl (1S,5R)-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylate (Example 1).
Sources & evidence
- ORD record
- ord-5be906069f4340c18af9738dff8ec30c
- Source dataset
- uspto-grants-2003_05
- Patent number
- US06566355B1
Reaction notes
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