HCID 22472763, compound → HCID 10690840, compound

HRID 413071Notes

Reaction equation

HRID 413071 reaction equation
[Si:1]([N:8]1[C:14](=[O:15])[C@@H:13]2[C@H:9]1[C@@H:10]([OH:26])[CH2:11][N:12]2[C:16]([O:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:17])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].CC(C([O-])=O)CCCCC>>[CH2:19]([O:18][C:16]([N:12]1[CH2:11][C:10](=[O:26])[C@@H:9]2[C@H:13]1[C:14](=[O:15])[N:8]2[Si:1]([C:4]([CH3:6])([CH3:5])[CH3:7])([CH3:2])[CH3:3])=[O:17])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 22472763HCID 22472763, compoundHCID 67753907HCID 67753907, compound

Product 1

HCID 10690840HCID 10690840, compound

Procedure

(1S,5S)-6-(t-Butyl-dimethyl-silanyl)-4,7-dioxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester was prepared from benzyl (1S,4S,5S)-6-(t-butyldimethylsilanyl)-4-hydroxy-7-oxo-2,6-diazabicyclo[3.2.0]heptane-2-carboxylate in the same manner as described for benzyl (1S,5S)-6-(3,4-dimethoxybenzyl)-4,7-dioxo-2,6-diazabicyclo[3.2.0.]heptane-2-carboxylate (Example 7).

Sources & evidence

ORD record
ord-d148ae20737c4cbbb7a97427c56cac75
Source dataset
uspto-grants-2003_05
Patent number
US06566355B1

Reaction notes

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