HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 6-(3-Chloro-phenyl)4-ethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | HCID 23509612 | HCID 23509612 | — |
| Product | 6-(3-Chloro-phenyl)4-ethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one | HCID 9838874 | — |
Reaction Steps
Prepared according to the procedure of Example 9 from 1-(4-amino-3′-chloro-biphenyl-3-yl)-propanol and triphosgene. White solid: mp 146-148° C.; 1H-NMR (DMSO-d6) δ10.3 (s, 1H), 7.70 (m, 1H), 7.60 (m, 3H), 7.47 (t, 1H, J=8.22 Hz), 7.39 (d, 1H, J=8.28 Hz), 6.97 (d, 1H, J=8.22 Hz), 5.4 (t, 1H, J=10.9 Hz), 1.9 (m, 2H), 0.97 (t, 3H, J=7.68 Hz); MS (ESI) m/z 286 ([M−H]−, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06566358B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-138c06f7b956463da217f4d2929137e6 |
| Source note | uspto-grants-2003_05 |