HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 6-(3-Chloro-phenyl)4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 1-(4-Amino-3'-chloro-biphenyl-3-yl)-benzyl alcohol | HCID 68943743 | — |
| Product | 6-(3-Chloro-phenyl)4-phenyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one | HCID 9819111 | — |
Reaction Steps
Prepared from 1-(4-amino-3′-chloro-biphenyl-3-yl)-benzyl alcohol and triphosgene according to the procedure of Example 9. Off-white solid: mp 177-178° C.; 1H-NMR (DMSO-d6) δ10.5 (s, 1H), 7.68 (dd, 1H, J=8.7, 1.7 Hz), 7.62 (t, 1H, J=1.74 Hz), 7.54-7.5 (m, 1H), 7.48-7.34 (m, 8H), 7.04 (d, 1H, J=8.7 Hz), 6.6 (s,1H); MS (ESI) m/z 336 ([M+H]+, 30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06566358B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-c65fb763edd347078b43308efe198ac9 |
| Source note | uspto-grants-2003_05 |