Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-bromobenzonitrile → 4-Amino-3'-chloro-biphenyl-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-bromobenzonitrile | HCID 429740 | — |
| 반응물 | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| 생성물 | 4-Amino-3'-chloro-biphenyl-3-carbonitrile | HCID 9794575 | — |
반응 단계
Prepared from 2-amino-5-bromobenzonitrile and 3-chlorophenyl boronic acid according to procedure A. Off-white solid: mp 118-119° C.; 1H-NMR (DMSO-d6) δ7.80 (d, 1H, J=2.3 Hz), 7.65-7.72 (m, 2H), 7.57 (d, 1H, J=8.0 Hz), 7.42 (t, 1H, J=7.9 Hz), 7.31 (m, 1H), 6.87 (d, 1H, J=8.7 Hz), 6.29 (br, 2H); Anal. Calc. For C13H9ClN2: C, 68.28, H, 3.97, N, 12.25. Found: C, 67.68, H, 4.06, N, 11.89.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06566358B2 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-536536fb2320486c8d01e174dcc7cca3 |
| 출처 메모 | uspto-grants-2003_05 |