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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413156Generated: October 29, 2026

1,3-Dibromo-5-(trifluoromethoxy)benzene → HCID 10273358, compound

https://huagongshe.com/reaction/413156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Dibromo-5-(trifluoromethoxy)benzeneHCID 2761179—
Reactant(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acidHCID 10987806—
ProductHCID 10273358HCID 10273358—

Reaction Steps

Prepared from (4,4-dimethyl-1,4-dihydro-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid and 1, 3-dibromo-5-trifluoromethoxybenzene according to Procedure B. White solid: mp 214-216° C.; 1H-NMR (DMSO-d6) δ10.4 (s, 1H), 7.99 (s, 1H), 7.73 (s, 1H), 7.68-7.62 (m, 3H), 6.97 (d, 1H, J=8.0 Hz), 1.68 (s, 6H); MS (ESI) m/z 414 ([M−H]−, 100%); Anal. Calc. For C17H13BrF3NO3: C, 49.06, H, 3.15, N, 3.37. Found: C, 49.16, H, 3.05, N, 3.30.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06566358B2
Source datasetuspto-grants-2003_05
ORD IDord-4263f8a92b604838bcb414ad213283a3
Source noteuspto-grants-2003_05