HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Bromo-2-fluorophenyl)acetonitrile → HCID 23509618, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Bromo-2-fluorophenyl)acetonitrile | HCID 7172308 | — |
| Reactant | (4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid | HCID 10987806 | — |
| Product | HCID 23509618 | HCID 23509618 | — |
Reaction Steps
Prepared according to procedure B from 4-bromo-2-fluorophenylacetonitrile (T. Alessi A. H. P. U.S. Pat. No: 4,895,862) and (1,4-dihydro-4,4-dimethyl-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid. A grey solid; mp 253-256° C. 1HNMR(DMSO-d6) □10.35 (s,1H) 7.67-7.49(m,5H), 6.97(d,1H; J=8.6 Hz) 4.09 (s,2H) (s,2H) 1.67(s,6H); MS [M−H]− m/z 309. Anal. Calc. For C18H15N2FO2.0.15H20: C,69.07, H, 4.93, N, 8.95. Found C,69.27, H 5.05, N, 8.50
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06566358B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-364f003385214c90bfa739fa6e73151e |
| Source note | uspto-grants-2003_05 |