HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-[4-(trifluoromethylsulfonyl)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Aminophenyl trifluoromethyl sulphone | HCID 136315 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | N-[4-(trifluoromethylsulfonyl)phenyl]acetamide | HCID 459394 | — |
Reaction Steps
Reflux 4-trifluoromethylsulfonyl-phenylamine (5 g) and Ac2O (2.2 mL) for 1.5 hours in HOAc (20 mL). Evaporate the solvent in vacuo, then crystallize the residue in EtOAc/EtOH to obtain N-(4-trifluoromethylsulfonyl-phenyl)-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06566367B2 |
| Source dataset | uspto-grants-2003_05 |
| ORD ID | ord-125f61f384cb41d79571437b1b5a78a5 |
| Source note | uspto-grants-2003_05 |