Triethylamine → 2,3-Dihydro-1H-indole-1-carbonyl chloride

Participants

Reaction Conditions

Reaction Steps

22.5 mmol of diphosgene dissolved in 90 ml of dichloromethane are cooled to 0° C.; there are then added 45 mmol of indoline, and then 67.5 mmol of triethylamine, while maintaining the temperature at 0° C. After 12 hours at ambient temperature, the mixture is filtered and the filtrate is concentrated under reduced pressure.

Provenance & Evidence