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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413283Generated: October 28, 2026

Benzyl Bromide → 1-benzyl-1H-pyrazole-3-carbaldehyde

https://huagongshe.com/reaction/413283

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantPotassium CarbonateHCID 11430—
Reactant1H-Pyrazole-3-carbaldehydeHCID 12218383—
SolventDimethylformamideHCID 6228—
Product1-benzyl-1H-pyrazole-3-carbaldehydeHCID 1140119961.9%

Reaction Steps

To a solution of benzyl bromide (0.29 g) in N,N-dimethylformamide (9 ml) was added 1H-pyrazole-3-carboxaldehyde (0.15 g) and potassium carbonate (0.24 g). The mixture was stirred at room temperature for 24 hours, silica gel was added, the solvent removed by evaporation and the crude material purified by chromatography (isohexane:ether, 2:1) to give the product as an oil (0.18 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06566376B1
Source datasetuspto-grants-2003_05
ORD IDord-6d33378c29d04b489b7fbd4671e4aa97
Source noteuspto-grants-2003_05