6-nitro-3H-benzo[1,2,3]oxathiazole 2,2-dioxide → 6-Amino-3H-benzo[1,2,3]oxathiazole 2,2-dioxide

Participants

Reaction Steps

A solution of 6-nitro-3H-benzo[1,2,3]oxathiazole 2,2-dioxide (example 5) (8.1 g, 37 mmol) in methanol (250 ml) is hydrogenated at atmospheric pressure in the presence of Pd-C. The catalyst is then filtered off, the clear solution is treated with methanolic HCl (1 N) and the solvent is distilled off under reduced pressure. The residue is dissolved in ethanol and the product crystallizes after addition of diethyl ether.

Provenance & Evidence