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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413373Generated: October 26, 2026

N-Methylaniline → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-(phenylamino)-pentanoic Acid

https://huagongshe.com/reaction/413373

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylanilineHCID 7515—
ReactantMethyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 12073922—
Product2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-(phenylamino)-pentanoic AcidHCID 9869333—

Reaction Steps

Example 21 is prepared from N-methylaniline and 1d using the procedure described for compound 19.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06566381B1
Source datasetuspto-grants-2003_05
ORD IDord-70a0e2ddbe7a4724b09019245925e3ec
Source noteuspto-grants-2003_05