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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 413374Generated: October 29, 2026

Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[(2-imidazolyl)thio]-pentanoic Acid

https://huagongshe.com/reaction/413374

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 12073922—
ReactantHCID 178527877HCID 178527877—
Product2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[(2-imidazolyl)thio]-pentanoic AcidHCID 23508288—

Reaction Steps

Example 22 is prepared from 2-mercaptoimidazole and 1d using the procedure described for compound 20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06566381B1
Source datasetuspto-grants-2003_05
ORD IDord-75077651518f416489e4bf2aabac2d79
Source noteuspto-grants-2003_05