2-Thiophenethiol → HCID 18532988, compound

HRID 413383Notes

Reaction equation

HRID 413383 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[SH:6].[CH3:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([S:21]([NH:24][CH:25]([CH2:30][CH:31]3[O:33][CH2:32]3)[C:26]([O:28]C)=[O:27])(=[O:23])=[O:22])=[CH:17][CH:16]=2)=[CH:11][CH:10]=1>>[CH3:7][O:8][C:9]1[CH:10]=[CH:11][C:12]([C:15]2[CH:16]=[CH:17][C:18]([S:21]([NH:24][CH:25]([CH2:30][CH:31]([OH:33])[CH2:32][S:6][C:2]3[S:1][CH:5]=[CH:4][CH:3]=3)[C:26]([OH:28])=[O:27])(=[O:22])=[O:23])=[CH:19][CH:20]=2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 5226742-ThiophenethiolHCID 12073922Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate

Product 1

HCID 18532988HCID 18532988, compound

Procedure

Example 34 is prepared from 2-thiophenethiol and 1d using the procedure described for compound 20.

Sources & evidence

ORD record
ord-1b6bbe777361430c8f19d718a4fc7030
Source dataset
uspto-grants-2003_05
Patent number
US06566381B1

Reaction notes

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