Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → HCID 23508280, compound

HRID 413386Notes

Reaction equation

HRID 413386 reaction equation
[CH3:1][S:2][C:3]1[N:7]=[C:6]([SH:8])[S:5][N:4]=1.[CH3:9][O:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[CH:22]=[CH:21][C:20]([S:23]([NH:26][CH:27]([CH2:32][CH:33]3[O:35][CH2:34]3)[C:28]([O:30]C)=[O:29])(=[O:25])=[O:24])=[CH:19][CH:18]=2)=[CH:13][CH:12]=1>>[CH3:9][O:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[CH:18]=[CH:19][C:20]([S:23]([NH:26][CH:27]([CH2:32][CH:33]([OH:35])[CH2:34][S:8][C:6]3[S:5][N:4]=[C:3]([S:2][CH3:1])[N:7]=3)[C:28]([OH:30])=[O:29])(=[O:24])=[O:25])=[CH:21][CH:22]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 12073922Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 178503622HCID 178503622, compound

Product 1

HCID 23508280HCID 23508280, compound

Procedure

Example 38 is prepared from 3-methylmercapto-5-mercapto-1,2,4-thiadiazole and 1d using the procedure described for compound 20.

Sources & evidence

ORD record
ord-424d8289c15a42cf9aa2c1c6fc5fc62a
Source dataset
uspto-grants-2003_05
Patent number
US06566381B1

Reaction notes

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