Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → 2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[4,6-dimethylpyrimidin-2-ylthio]-pentanoic Acid

Participants

Role	Name	HCID	Charge
Reactant	Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate	HCID 12073922	—
Reactant	4,6-dimethylpyrimidine-2-thiol	HCID 178426632	—
Product	2-[(4'-Methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4-hydroxy-5-[4,6-dimethylpyrimidin-2-ylthio]-pentanoic Acid	HCID 23508279	—

Example 46 is prepared from 4,6-dimethyl-2-mercaptopyrimidine and 1d using the procedure described for compound 20.