Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate → HCID 23508274, compound

HRID 413394Notes

Reaction equation

HRID 413394 reaction equation
[SH:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[CH:4][N:3]=1.[CH3:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][C:22]([S:25]([NH:28][CH:29]([CH2:34][CH:35]3[O:37][CH2:36]3)[C:30]([O:32]C)=[O:31])(=[O:27])=[O:26])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1>>[CH3:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]2[CH:20]=[CH:21][C:22]([S:25]([NH:28][CH:29]([CH2:34][CH:35]([OH:37])[CH2:36][S:1][C:2]3[N:10]=[C:9]4[C:5]([NH:6][CH:7]=[N:8]4)=[CH:4][N:3]=3)[C:30]([OH:32])=[O:31])(=[O:26])=[O:27])=[CH:23][CH:24]=2)=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 12073922Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoateHCID 178527849HCID 178527849, compound

Product 1

HCID 23508274HCID 23508274, compound

Procedure

Example 48 is prepared from 2-mercaptopurine and 1d using the procedure described for compound 20.

Sources & evidence

ORD record
ord-0f99a61f83c4408aba68e8fbba36e27f
Source dataset
uspto-grants-2003_05
Patent number
US06566381B1

Reaction notes

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