4-Methoxy-alpha-toluenethiol → HCID 18532990, compound

HRID 413396Notes

Reaction equation

HRID 413396 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][SH:10])=[CH:5][CH:4]=1.[CH3:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[CH:24]=[CH:23][C:22]([S:25]([NH:28][CH:29]([CH2:34][CH:35]3[O:37][CH2:36]3)[C:30]([O:32]C)=[O:31])(=[O:27])=[O:26])=[CH:21][CH:20]=2)=[CH:15][CH:14]=1>>[CH3:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]2[CH:20]=[CH:21][C:22]([S:25]([NH:28][CH:29]([CH2:34][CH:35]([OH:37])[CH2:36][S:10][CH2:9][C:6]3[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)[C:30]([OH:32])=[O:31])(=[O:26])=[O:27])=[CH:23][CH:24]=2)=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 804074-Methoxy-alpha-toluenethiolHCID 12073922Methyl 2-[(4'-methoxy[1,1'-biphenyl]-4-yl)sulfonyl]amino-4,5-epoxypentanoate

Product 1

HCID 18532990HCID 18532990, compound

Procedure

Example 50 is prepared from 4-methoxy-α-toluenethiol and 1d using the procedure described for compound 20.

Sources & evidence

ORD record
ord-2a97d270f8d24b5e95c491dd955199b9
Source dataset
uspto-grants-2003_05
Patent number
US06566381B1

Reaction notes

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