Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenol → Methyl-4-(trans-5-decenyloxy)-benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| 반응물 | 5-Decen-1-ol, (5E)- | HCID 5283292 | — |
| 반응물 | Diethyl azodicarboxylate | HCID 5462977 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Methyl-4-(trans-5-decenyloxy)-benzoate | HCID 18521058 | 72% |
반응 단계
DEAD (256 mg, 1.47 mmol), phenol 34 (194 mg, 1.28 mmol), alcohol 26j (200 mg, 1.28 mmol), and TPP (386 mg, 1.47 mmol) in 13 ml anhydrous ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5 to 90/10 (v/v, Hex/EtOAc). Evaporation of the solvent yielded 266 mg (72%) of colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06569504B1 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-f88af62debeb4184a7fbf0620da384ed |
| 출처 메모 | uspto-grants-2003_05 |