反应详情

To a 70° C. solution of 25 grams (0.125 mole) of 4,4′-diaminodiphenyl ether in 90 ml of glacial acetic acid was added 28.55 ml (0.286 mole) of acetic anhydride. The acetic anhydride was added dropwise at such a rate and with heating to maintain a temperature between 90° C. and 100° C. After the addition of acetic anhydride, the temperature was maintained between 90° C. and 100° C. for an additional hour. The reaction mixture was further reacted at room temperature overnight forming a precipitate. The mixture was filtered, and the collected precipitate dried at room temperature to give 32.6 grams of 4,4′-diacetamidodiphenyl ether, m.p. 228-230° C. (lit. m.p. 228-229° C.). The yield was 91.8% of the theoretical amount.

1. temperaturewith heating
2. temperatureto maintain a temperature between 90° C. and 100° C
3. temperaturethe temperature was maintained between 90° C. and 100° C. for an additional hour
4. customThe reaction mixture was further reacted at room temperature overnight
5. customforming a precipitate
6. filtrationThe mixture was filtered
7. customthe collected precipitate dried at room temperature